{"id":48127,"date":"2016-07-06T00:01:51","date_gmt":"2016-07-05T16:01:51","guid":{"rendered":"https:\/\/tw-taiwannews.com\/?p=48127"},"modified":"2016-07-06T10:35:52","modified_gmt":"2016-07-06T02:35:52","slug":"%e9%ab%98%e9%86%ab%e6%aa%a2%e9%a9%97%e9%86%ab%e5%ad%b8%e9%83%a8%e9%81%ba%e5%82%b3%e5%ae%a4%e4%b8%bb%e4%bb%bb%e5%8a%89%e5%a4%a7%e6%99%ba%ef%bc%9a%e6%b6%b2%e6%85%8b%e7%94%9f%e7%89%a9%e6%aa%a2%e9%ab%94","status":"publish","type":"post","link":"https:\/\/tw-taiwannews.com\/?p=48127","title":{"rendered":"\u9ad8\u91ab\u6aa2\u9a57\u91ab\u5b78\u90e8\u907a\u50b3\u5ba4\u4e3b\u4efb\u5289\u5927\u667a\uff1a\u6db2\u614b\u751f\u7269\u6aa2\u9ad4 \u80ba\u764c\u57fa\u56e0\u6aa2\u6e2c\u65b0\u5229\u5668"},"content":{"rendered":"<p><span style=\"color: #0000ff;\"><strong>\u9ad8\u91ab\u6aa2\u9a57\u91ab\u5b78\u90e8\u907a\u50b3\u5ba4\u4e3b\u4efb\u5289\u5927\u667a\uff1a\u6db2\u614b\u751f\u7269\u6aa2\u9ad4 \u80ba\u764c\u57fa\u56e0\u6aa2\u6e2c\u65b0\u5229\u5668<\/strong><\/span><\/p>\n<p><span style=\"color: #0000ff;\"><strong>\u6aa2\u9a57\u91ab\u5b78\u90e8\u5206\u5b50\u7d30\u80de\u75c5\u7406\u53ca\u907a\u50b3\u5ba4\u5728\u937e\u98f2\u6587\u9662\u9577\u7684\u5927\u529b\u652f\u6301\u6210\u6548\u4eae\u773c<\/strong><\/span><\/p>\n<p><span style=\"color: #000000;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u59dc\u745e\u65af \/ \u6839\u64da\u884c\u653f\u9662\u885b\u798f\u90e8\u570b\u6c11\u5065\u5eb7\u7f72\u6c11\u570b103\u5e74\u764c\u75c7\u767b\u8a18\u5831\u544a\u986f\u793a\uff0c\u80ba\u764c\u4f4d\u5c45\u570b\u4eba\u4e3b\u8981\u764c\u75c7\u6b7b\u4ea1\u7387\u6392\u884c\u4e4b\u9996\uff0c\u7576\u5e74\u5168\u570b\u80ba\u764c\u767c\u751f\u4eba\u657811751\u540d\uff0c\u6b7b\u4ea1\u4eba\u6578\u70ba9,167\u540d\uff0c\u4f54\u6240\u6709\u764c\u75c7\u6b7b\u4ea1\u4eba\u6578\u7684 19.9\uff05\uff0c\u4e14\u80ba\u764c\u6b7b\u4ea1\u4eba\u6578\u6709\u9010\u5e74\u589e\u52a0\u4e4b\u8da8\u52e2\u3002\u5728\u570b\u5167\u7f79\u60a3\u80ba\u764c\u7684\u75c5\u4eba\u4e2d\uff0c\u8d85\u904e\u516d\u6210\u7684\u6bd4\u4f8b\u70ba\u80ba\u817a\u764c\u3002\u65e9\u671f\u80ba\u817a\u764c\u4e26\u7121\u660e\u986f\u75c7\u72c0\uff0c\u591a\u662f\u5728\u816b\u7624\u58d3\u8feb\u81f3\u6b63\u5e38\u5668\u5b98\u6216\u7d44\u7e54\u6642\uff0c\u60a3\u8005\u624d\u6703\u5bdf\u89ba\u7570\u72c0\uff0c\u56e0\u6b64\u7d04\u670975% \u7684\u75c5\u4eba\u5728\u5c31\u91ab\u6642\uff0c\u75c5\u60c5\u5df2\u767c\u5c55\u70ba\u665a\u671f\u80ba\u817a\u764c (IIIB, IV\u671f)\u3002\u665a\u671f\u80ba\u817a\u764c\u591a\u534a\u4e0d\u9069\u5408\u624b\u8853\u6cbb\u7642\uff0c\u4e3b\u8981\u7684\u6cbb\u7642\u65b9\u5f0f\u662f\u4ee5\u6a19\u9776\u6cbb\u7642\u53ca\u5316\u5b78\u6cbb\u7642\u70ba\u4e3b\uff0c\u9019\u985e\u75c5\u4eba\u7d04\u670960\uff05\u6709\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\uff08EGFR\uff09\u81f4\u764c\u57fa\u56e0\u7a81\u8b8a\uff0c\u53ef\u5148\u7528\u6a19\u9776\u85e5\u7269\u6cbb\u7642\u3002\u53ef\u60dc\u7684\u662f\u6a19\u9776\u85e5\u7269\u5e73\u574712\u500b\u6708\u5f8c\u5c31\u6703\u7522\u751f\u6297\u85e5\u6027\uff0c\u4e5f\u5c31\u662f\u8b93\u816b\u7624\u8b8a\u5c0f\u6216\u6d88\u5931\u4e00\u6bb5\u6642\u9593\uff0c\u4e4b\u5f8c\u7642\u6548\u53c8\u958b\u59cb\u8b8a\u5dee\u4e86\uff0c\u816b\u7624\u9577\u5f97\u66f4\u5927\u6216\u8f49\u79fb\u5230\u5176\u4ed6\u5730\u65b9\u3002\u7814\u7a76\u986f\u793a\u7522\u751f\u6297\u85e5\u6027\u7684\u75c5\u4eba\u4e2d\u6709\u4e00\u534a\u4ee5\u4e0a(60% )\u662f\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\uff08EGFR\uff09\u7522\u751f\u4e86\u65b0\u7684\u7a81\u8b8a (T790M) \uff0c\u4e5f\u5c31\u662fEGFR\u81f4\u764c\u57fa\u56e0\u7684\u7b2c790\u500b\u6c28\u57fa\u9178\u7531\u8607\u6c28\u9178(threonine)\u7a81\u8b8a\u70ba\u86cb\u6c28\u9178(Methionine)\uff0c\u5c0e\u81f4\u7b2c\u4e00\u53ca\u7b2c\u4e8c\u4ee3\u7684\u6a19\u9776\u85e5\u7269\u7121\u6548\u3002\u6240\u5e78\u76ee\u524d\u5df2\u6709\u91dd\u5c0dT790M\u7a81\u8b8a\u7684\u7b2c\u4e09\u4ee3\u6a19\u9776\u85e5\u7269\u53ef\u7528\uff0c\u5176\u4e2d\u4f4d\u75be\u75c5\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u70ba9.6~ 13.1\u500b\u6708\u3002<\/span><br \/>\n<span style=\"color: #000000;\">\u76ee\u524d\u6aa2\u6e2cT790M\u7a81\u8b8a\u4ecd\u7136\u4ee5\u7d44\u7e54\u5207\u7247\u6216\u958b\u5200\u75c5\u7406\u6aa2\u9ad4(\u881f\u584a\u6aa2\u9ad4)\u70ba\u4e3b\uff0c\u5982\u524d\u6240\u8ff0\uff0c\u75c5\u4eba\u5927\u90fd\u662f\u665a\u671f\u80ba\u817a\u764c\u53c8\u75be\u75c5\u60e1\u5316\uff0c\u8eab\u9ad4\u72c0\u6cc1\u904e\u65bc\u865b\u5f31\u7121\u6cd5\u627f\u53d7\u9032\u4e00\u6b65\u7684\u7d44\u7e54\u5207\u7247\u6216\u958b\u5200\uff0c\u5c0e\u81f4\u6c92\u6709\u6a5f\u6703\u63a5\u53d7\u7b2c\u4e09\u4ee3\u6a19\u9776\u85e5\u7269\u6cbb\u7642\uff0c\u55aa\u5931\u4e86\u53ef\u4ee5\u5ef6\u9577\u58fd\u547d\u53ca\u6539\u5584\u751f\u6d3b\u54c1\u8cea\u7684\u5927\u597d\u6a5f\u6703\uff0c\u6240\u4ee5\u6aa2\u9a57\u91ab\u5b78\u90e8\u5206\u5b50\u7d30\u80de\u75c5\u7406\u53ca\u907a\u50b3\u5ba4\u5728\u937e\u98f2\u6587\u9662\u9577\u7684\u5927\u529b\u652f\u6301\u4e0b\uff0c\u7a4d\u6975\u7814\u767c\u65b0\u6aa2\u9a57\u65b9\u6cd5\uff0c\u767c\u5c55\u4e86\u6db2\u614b\u751f\u7269\u6aa2\u9ad4\u6aa2\u6e2c\u3002<\/span><br \/>\n<span style=\"color: #000000;\">\u6db2\u614b\u751f\u7269\u6aa2\u9ad4\uff0c\u53ea\u8981\u900f\u904e\u62bd\u884010ml\uff0c\u5373\u53ef\u5075\u6e2c\u75c5\u4eba\u8840\u6db2\u4e2d EGFR T790M\u7a81\u8b8a (\u7576\u7136\u4e5f\u53ef\u6e2c\u5176\u4ed6EGFR\u57fa\u56e0\u7684\u7a81\u8b8a)\u3002\u4e0d\u50c5\u70ba\u7121\u6cd5\u9032\u884c\u7d44\u7e54\u5207\u7247\u7684\u75c5\u4eba\u5e36\u4f86\u798f\u97f3\uff0c\u4e5f\u80fd\u900f\u904e\u6aa2\u6e2c\u7d50\u679c\u9078\u64c7\u6709\u6548\u7684\u6cbb\u7642\u6a5f\u6703\u3002\u65bc2016\u5e744\u6708\u901a\u904e\u6db2\u614b\u751f\u7269\u6aa2\u9ad4\u80fd\u529b\u8a66\u9a57\u5f8c, \u8fc42016\u5e746\u6708\u5e95\u5171\u6aa2\u6e2c60\u4f8b\u80ba\u817a\u764c\u60e1\u5316\u7684\u75c5\u4eba\u5468\u908a\u8840\u6aa2\u9ad4 (liquid biopsy) \uff0c \u5176\u4e2d\u670925\u4f8b\u66fe\u53d7\u6aa2\u6709\u7a81\u8b8a\u8005\uff0c\u6cbb\u7642\u5f8c\u75c5\u60c5\u60e1\u5316\uff0c\u6aa2\u6e2c\u7d50\u679c\u767c\u73fe44% (11\/25) \u9664\u4e86\u539f\u7a81\u8b8a\u578b\u5916\u9084\u51fa\u73feT790M\u7a81\u8b8a\u3002\u9019\u4e9b\u75c5\u4eba\u90fd\u6709\u6a5f\u6703\u63a5\u53d7\u7b2c\u4e09\u4ee3\u6a19\u9776\u85e5\u7269\u6cbb\u7642\u30022016\/07\/06<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9ad8\u91ab\u6aa2\u9a57\u91ab\u5b78\u90e8\u907a\u50b3\u5ba4\u4e3b\u4efb\u5289\u5927\u667a\uff1a\u6db2\u614b\u751f\u7269\u6aa2\u9ad4 \u80ba\u764c\u57fa\u56e0\u6aa2\u6e2c\u65b0\u5229\u5668 \u6aa2\u9a57\u91ab\u5b78\u90e8\u5206\u5b50\u7d30\u80de\u75c5\u7406\u53ca\u907a\u50b3\u5ba4\u5728\u937e\u98f2\u6587\u9662\u9577\u7684 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":48128,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"_links":{"self":[{"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/posts\/48127"}],"collection":[{"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48127"}],"version-history":[{"count":0,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/posts\/48127\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=\/wp\/v2\/media\/48128"}],"wp:attachment":[{"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48127"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=48127"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tw-taiwannews.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=48127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}